Why are PO ratios not necessarily integral A PO ratios depen

Why are P/O ratios not necessarily integral?

A.) P/O ratios depend upon the ratios of the individual complexes. B.) P/O ratios depend upon the source of the mitochondria. C.) Not all of the protons translocated will be used for ATP synthesis, in part due to proton leakage. D.) Under some circumstances more protons are necessary for ATP synthesis.

In yeast, influx of 10 protons through the membrane bound portion of the proton-translocating ATP synthase is sufficient to drive the synthesis of about 3 ATP. True or False

Solution

1) The P/O ratio not necessary integral because not all protons translocated will be used for ATP synthesis, in part due to proton leakage.   

2) false