1 Mr G is a 64yearold man who has been admitted to the coron

1.     Mr. G. is a 64-year-old man who has been admitted to the coronary care unit because he is experiencing heart failure. He has been given 80 mg of furosemide q6h but has experienced no relief of the pulmonary and peripheral edema. The physician would like to change his diuretic to bumetanide. What is the equivalent daily dose of bumetanide? References your findings.

Solution

The above old-man has suffering from heart failure with the pulmonary and peripheral edema due to high fluid accumulation so that it is essential eliminate excess fluid accumulation using loop diuretics. So that, \"80mg\" furesemide has given lower affects to relieve the pulmonary and peripheral edema

Therefore, as per bioavailability studies, 1 mg bumetanide ----> equivalent to 40 mg furosemide

So that, the conversion ratio ---> 40 mg furosemide to 1 mg bumetanide

                                          ---> 80mg furosemide to \"2 mg the equivalent daily dose \" bumetanide