5 Which of the following statements regarding thermodynamics

5. Which of the following statements regarding thermodynamics is TRUE:

1- G°is always equivalent to G°in normal body conditions

2- A biochemical reaction with a negative G° if taken place in the cell will always

release energy

3- A positive G in the cell indicates that the reaction can go forward

4- Consumption of products in a reaction can cause a positive G reaction to

proceed

5- 3 and 4

Solution

2. A biochemical reaction with a negative G° if taken place in the cell will always release energy.

Delta G= Free energy (Final) - Free Energy (Initial)

Negative Delta G means Initial Free energy is greater than Final. When a reaction has greater energy in the beginning, it will have to release energy to reach a lower value.