Which of the following factors determine an enzymes specific

Which of the following factors determine an enzyme\'s specificity? The Michaelis constant The type of cofactor required for the enzyme to be active The prosthetic group of the enzyme The three-demensional shape of the active site

Solution

D. The three dimensional shape of active site.

An enzyme\'s specificity is determined by the 3 dimensional shape of its active site. Regardless of which theory of enzyme specificity we are discussing (lock and key or induced fit), the active site determines which substrate the enzyme will react with.