BIOINFORMATICS EXPLAIN WHICH OF THE FOLLOWING FRAMES OF AMIN

BIOINFORMATICS

EXPLAIN WHICH OF THE FOLLOWING FRAMES OF AMINO SEQUENCES ARE VALID AND HOW DID YOU KNOW?

5\'3\' Frame 1

S E S R S I I F N Met E R I K E L R N L Met S Q S R T R E I L T K T T V D H Met A I I K K Y T S G R Q E K N P A L R P A L S I N E L S N L A K G E

5\'3\' Frame 2

A K A G Q L Y S I W K E Stop K N Stop E I Stop C R S L A P A R Y S Q K P P W T I W P Stop S R S T H Q E D R R R T Q H L G Q H Stop A S Met N Stop A T L R K E

5\'3\' Frame 3

R K Q V N Y I Q Y G K N K R T K K S N V A V S H P R D T H K N H R G P Y G H N Q E V H I R K T G E E P S T Stop A S I K H Q Stop T E Q P C E R R

3\'5\' Frame 1

L S F R K V A Q F I D A Stop C W P K C W V L L L S S Stop C V L L D Y G H Met V H G G F C E Y L A G A R L R H Stop I S Stop F F Y S F H I E Y N Stop P A F A

3\'5\' Frame 2

S P F A R L L S S L Met L N A G L S A G F F S C L P D V Y F L I Met A I W S T V V F V S I S R V R D C D I R F L S S F I L S I L N I I D L L S

3\'5\' Frame 3

L L S Q G C S V H Stop C L Met L A Stop V L G S S P V F L Met C T S Stop L W P Y G P R W F L Stop V S R G C E T A T L D F L V L L F F P Y Stop I Stop L T C F R

Solution

Answer: 5\'3\' Frame 1

S E S R S I I F N Met E R I K E L R N L Met S Q S R T R E I L T K T T V D H Met A I I K K Y T S G R Q E K N P A L R P A L S I N E L S N L A K G E

An open reading frame contain a strech of codons that has the potential to be translated. Translation stats with AUG codan, which codes for Met amino acid and it is not necessory to be at1st position. It do not contain stop codan and it should be in 5\' to 3\' orientation.