Homework SourseDrug X binds to plasma protein fu 7 and has a total clearanc
Drug X binds to plasma protein (fu= .7) and has a total clearance of 500 min/ml with 75% of the dose excreted unchanged. What is the renal clearance? What is the non-renal clearance?
Drug X binds to plasma protein (fu= .7) and has a total clearance of 500 min/ml with 75% of the dose excreted unchanged. What is the renal clearance? What is the non-renal clearance?
Solution
renal clearance= total clearance x dose excretes unchanged here/ plasmaprotein
=500x75/100 /0.7=535.71
non renal clearance=1000-535.71=>464.29
