A If cultured human cells such as HeLa cells replicate 12 m

A. If cultured human cells (such as HeLa cells) replicate 1.2 m of DNA during a five-hour S phase and at a rate of fork movement one-tenth of that seen in E.coli, how many origins of replication must the cells contain? Express your answers using four significant figures.

B. What is the average distance, in kilobase pairs, between these origins? Express your answers using four significant figures.

Solution

A) Rate=1/10* E.COLI=1/10*1.2=>0.12

origins=rate*numbr of hours*100=>0.12*5=0.60*100=60

B)the average distance between pairs =RATE- replication=1.2-0.12=1.08m