Which of these is not true about the betagamma subunit of th

Which of these is not true about the beta-gamma subunit of the heterotrimeric G protein often coupled to 7TM-receptors?

Provide explanations for the answers you choose and do not choose.

A. it does not change conformations

B. when in heterotrimeric form, it increases affinity of alpha subunit for GDP

C. it consists of the GTPase domain and the alpha helical domain

D. the subunits are bound together by covalently attached lipid molecules

Solution

G proteins are comprised of 2 subunits. Those are 1. Alfa; 2. Beta-Gama dimer. When alfa subunit bind to GTP, Beta-Gama dimer dissociate and activities down stream signals

C is not true. Because GTPase activity observed in alfa sub units