Homework SourseWhich of the following enzymes has the ability to accomplish
Which of the following enzymes has the ability to accomplish all three of the following: 1) cut DNA; 2) introduce and/or remove twists in the molecule; and 3) rejoin the cut ends of a DNA molecule?
| Restriction enzyme |
| Type I Topoisomerase |
| DNase I |
| Type II Topoisomerase |
Solution
Answer:
The type I topoisomerases are enzymes that cut one of the two strands of double-stranded DNA, relax the strand, and reanneal the strand. They are further subdivided into two structurally and mechanistically distinct topoisomerases: type IA and type IB.
| Type I Topoisomerase |
