Homework SourseConsider the following hydropathy plot for a multipass trans
Consider the following hydropathy plot for a multipass transmembrane protein in the ER membrane. The asterisk indicates the position of some positively-charged amino acids. Which of the following is likely to be true?
Both the C-terminus and the N-terminus are in the cytosol
Both the C-terminus and the N-terminus are in the ER lumen
The C-terminus will be in the ER-lumen and the N-terminus is in the cytosol
none of the above
| A. | Both the C-terminus and the N-terminus are in the cytosol | |
| B. | Both the C-terminus and the N-terminus are in the ER lumen | |
| C. | The C-terminus will be in the ER-lumen and the N-terminus is in the cytosol | |
| D. | none of the above |
Solution
Option C: The C-terminus will be in the ER-lumen and the N-terminus is in the cytosol
