Why does DNA polymerase III exist as a dimerSolutionThe DNA
Why does DNA polymerase III exist as a dimer?
Solution
The DNA polymerase III contains two cores held together by a ? dimer. This coupling tethers the lagging strand polymerase to the fork. This enables the recycling through the successive rounds of Okazaki fragment synthesis. Also, the core has two essential subunits: the ? subunit links the nucleotides, and the ? subunit ensures that they are accurate. Due to the presence of two cores, DNA polymerase III is known as dimer. The multiple subunits of DNA polymerase III work together to synthesize a new strand of DNA.
