Sketched below are the concentration profiles of a protein i

Sketched below are the concentration profiles of a protein (in an aqueous solution) diffusing across an uncharged membrane. For each indicate whether the partition coefficient is less than unity, equal to unity or greater than unity.

(b) Which of the profiles sketched are possible?

Solution

Partition Coefficient, P = [Organic] / [Aqueous] the more the P value means the more solubility in organic solvents and less than one means the water loving nature of the compound or the drug. So all the conditions have the log P value below one. The possibility of C is more based on the diffusion model.