SHOW WORK EXPLAIN 8 Determine the modes of inheritance poss

(SHOW WORK & EXPLAIN)

8. Determine the mode(s) of inheritance possible for the following pedigrees. Fill in the genotype for as many individuals as possible. If a mode impossible, indicate where the pedigree \"doesn\'t fit\" with that mode of inheritance. a. Pedigree A

Solution

answer

a. autosomal recceive mode of inheritance

First pedigree

A--------NORMAL ALLELE       abnormal allele-a

Autosomal recessive mode of inheritance

I

I-1

I-2

geneotype

AA

aa

II

II-1

II-2

II-3

II-4

geneotype

Aa

Aa

Aa

Aa

III

III-1

III-2

III-3

geneotype

Aa

Aa

aa

II-1 x II-2

A

a

A

A

Aa

a

Aa

aa      affected

b .autosomal dominant mode of inheritance

Second pedigree

Autosomal dominant mode of inheritance

I

I-1

I-2

I-3

I-4

geneotype

Aa

Aa

aa

Aa

normal

II

II-5

II-6

II-7

II-8

II-8

geneotype

Aa

Aa

aa

aa

Aa

normal

normal

III

III-10

III-11

III-12

geneotype

aa--normal

aa-----normal

aa-----normal

======================================================

C autosomal reccsseive mode of inheritance

I	I-1	I-2
geneotype	AA	aa
II	II-1	II-2	II-3	II-4
geneotype	Aa	Aa	Aa	Aa
III	III-1	III-2	III-3
geneotype	Aa	Aa	aa