Consider a population with two genes each with two alleles Y

Consider a population with two genes, each with two alleles (Y, y, and Q, q). The frequency of Y is 0.23 and the frequency of Q is 0.41. The gametic frequency of YQ in the population is 0.13.

A. What are the expected gametic frequencies?

B. What is the D, the coefficient of linkage disequilibrium, for this pair of genes?

C. What are Dmin and Dmax?

D. If the recombination rate between the two genes is 0.12, how many generations will it take for the population to reach linkage equilibrium?

Solution

A) What are the expected gametic frequencies?

Ans:

Expected gametic frequencies are YQ,yQ,Yq,yq

B) What is the D, the coefficient of linkage disequilibrium, for this pair of genes?

Ans: D (deviation) = F_(YQ) * F _(yq) - F _(Yq) * F_(yQ) F=Frequency

If the two loci are in linkage disequilibrium, then D 0

C) What are Dmin and Dmax?

Ans: Dmax is the smaller of Yq and yQ

Dmin is the larger of –YQ and –yq