You have recently isolated a new virus and you determined t

_____ You have recently isolated a new virus and you determined that the virus is an enveloped, minus stranded RNA virus with a helical nucleocapsid. Where would you predict the receptors that the virus uses to attach to a cell are located? One of the proteins of the nucleocapsid One of the peplomers The RNA Could be either \"A\" or \"B\" None of the above

Solution

B. One of the peplomers.

A peplomer is a glycoprotein spike on a viral capsid or viral envelope. These protrusions will only bind to certain receptors on the host cell. They are essential for both host specificity and viral infectivity.

Negative-strand RNA viruses (NSV) includes Rhabdo-, Paramyxovirus, Orthomyxovirus and Many highly prevalent human pathogenic viruses such as the respiratory syncytial virus (RSV), parainfluenza viruses, influenza viruses, Ebola virus, These virus first infects the host cell by binding to the a host cell receptor through a viral surface glycoprotein.

Influenza virus is anegative-sense, single-stranded RNA virus. The nucleocapsid is helical.These viruses are enveloped and have two membrane glycoproteins ;

HA - hemagglutinin

NA - neuraminidase