Antibiotic resistance occurs when diseasecausing microbes be
Antibiotic resistance occurs when disease-causing microbes become resistant to antibiotic drug therapy. Because this resistance is typically genetic and transferred to the next generation of microbes, it is a very serious public health problem. According to the CDC, 7% of gonorrhea cases tested in 2004 were resistant to the antibiotic ciprofloxacin. A physician prescribed ciprofloxacin for the treatment of 18 cases of gonorrhea during one week in 2004.
 
 (a) What is the distribution of the cases resistant to ciprofloxacin?
 ---Select--- normal, standard normal, binomial, approximately normal with n =  and p =  (decimal)
 
 (b) What is the probability that exactly 1 out of the 18 cases were resistant to ciprofloxacin?
 (Use 3 decimal places.)
 
 (c) What is that probability for exactly 2 out of 18?
 (Use 3 decimal places.)
 
 (d) What is the probability that 1 or more out of the 18 were resistant to ciprofloxacin? (Hint: It is easier to first find the probability that exactly 0 of the 18 cases were resistant.)
 (Use 3 decimal places.)
 
 (e) What is the mean number of gonorrhea cases that are resistant to the antibiotic ciprofloxacin out of 18 cases?
= (Use 2 decimal places.)
 
 (f) What is the standard deviation  of the count of antibiotic-resistant cases?
= (Use 3 decimal places.)
Solution
a)
 Binomial Distribution
 b)
 PMF of B.D is = f ( k ) = ( n k ) p^k * ( 1- p) ^ n-k
 Where   
 k = number of successes in trials
 n = is the number of independent trials
 p = probability of success on each trial
 P( X = 1 ) = ( 18 1 ) * ( 0.07^1) * ( 1 - 0.07 )^17
 = 0.3669
 c)
 P( X = 2 ) = ( 18 2 ) * ( 0.07^2) * ( 1 - 0.07 )^16
 = 0.2348
 d)
 P( X < 1) = P(X=0)
 = ( 18 0 ) * 0.07^0 * ( 1- 0.07 ) ^18
 = 0.2708
 P( X > = 1 ) = 1 - P( X < 1) = 0.7292
 e)
 Mean ( np ) =1.26
 f)
 Standard Deviation ( npq )= 18*0.07*0.93 = 1.0825

