Information about Ebola is provided on the following pages A
Information about Ebola is provided on the following pages. After studying this information, outline the chain of infection by identifying the reservoir(s), portal(s) of exit, mode(s) of transmission, portal(s) of entry, and factors in host susceptibility.
Reservoirs:
Portals of exit:
Modes of transmission:
Portals of entry:
Factors in host susceptibility:
Solution
Still the natural reservoir of Ebola remains not identified and confirm but basis of evidence suggest that bats are the most likely reservoir.
Ebola exit from its reservoir through contact with body fluids to an infected animal.
Viral particles can be identified in all kind of body fluids suh as blood, tears, saliva, sputum, breast milk, diarrhea, vomit, urine, sweat and oil glands of the skin, and semen. therefore transmission occurs by contact of skin or mucus membranes with the body fluids of an infected person.
Virus ebola enters the body via breaks in the skin which have splashes on skin or mucus membranes.
Ebola finds its host cell via target on cell that is glycoproteins which helps absorption of the virus. Once it is entered cell it uncoats and replicating. It initially targets monocytes/macrophages that respond to the site of infection later via flow it goes to lymph nodes and then the liver and spleen. It then spreads throughout the body producing a cytotoxic effect in all infected cells.
