Microsatellites are genetic loci that do not code for protei

Microsatellites are genetic loci that do not code for proteins or regulate other genes, so we usually assume they are selectively neutral. You sample 100 individuals from a frog population and find the genotypes in the table below. What is the frequency of allele A in this population?

Solution

Answer: 70%

Hardy weinberg equation

p^2 +2pq+q^2=1

p^2=0.5

Square root of 0.5

p=0.7

Since we believe that the homozygous AA (p2) represents 50% (i.e. = 0.5), the square root (p) is 0.7 (70%).

frequency of allele A in this population is 70%