DNA isolated from a mouse cell contains 26 Thymine T Conside
DNA isolated from a mouse cell contains 26% Thymine (T). Considering the base-paring rules of DNA, what percent will be guanine (G) in this DNA?
a. 14%
b. 22%
c. 24%
d. 26%
e. 36%
Solution
Answer : The correct answer is C (24%). Given percentage of Thymine : 26 %, then Adenine percentage should be 26 %. based on this , Guanine constitutes 24% and cytosine will be 24 %.
Supplementary information : The results are based on chargoff\'s base equivalence rule which States that in DNA from any biological source the total amount of purines is always equal to the total amount of pyrimidines, more specifically, the amount of adenine is equal to the amount of tymine and the amount of guanine is equal to the amount of cytosine.
Or
Chargoff’s rule states that DNA from any cell of all organisms should have a 1:1 ratio of purines and pyrimidines
