There are 257 students in the course of which 40 follow twit

There are 257 students in the course, of which 40 follow twitter. What is the Delta G degree\' (units KJ/mol) for no twitter twitter? Assume temperature of 300K and RT = 2.5 KJ/mol. What is impact on O2 binding affinity if 23BPG is removed? What is Y (degree of saturation) for Mb if pO2 = 20 Torr? Recall that P50 for Mb is 2 Torr. Estimate Y for Hb at pO2 = 20 Torr. Assume n(hill) = 2.8 and P50 = 26 Torr

Solution

2). 2,3-BPG decreases the oxygen binding affinity of hemoglobin by decreasing its affinity for oxygen due to alteration in conformational changes, oxygen is loosely bound to hemoglobin in the presence of BPG. So, if 2,3-BPG is removed, no free oxygen will be available, oxygen binds to hemoglobin with high affinity.