Please answer the question carefully Briefly compare and con

Please answer the question carefully.

Briefly compare and contrast the three methods of obtaining fetal cells for testing.

Solution

Answer:

The three methods of obtaining fetal cells for prenatal diagnostic testing to unravel any presence of genetic diseases in the fetus:

1. Amniocentesis

2. Chorionic villus sampling (CVS)

3. Percutaneous umbilical blood sampling (PUBS)

The main comparison of these three methods for obtaining fetal cells are to analyze fetal karyotypes & number based or structure based chromosomal abnormalities to detect any presence of incidence of genetic disorders

The major contrast of these three methods:

CVS involves the insertion of a catheter into the intrauterine cavity in the direction of transabdominal or transvaginal finally useful to obtain fluid with fetal cells in the chorionic villi from the placenta followed by culturing of fetal cells. PUBS method is involve pacing a needle in the direction of transabdominal deeper into the uterus. This is followed by the process of phlebotomizing the umbilical cord to obtain fetal cells with no \"culturing of fetal cells\" for prenatal diagnosis. Amniocentesis is the process that contain insertion of a fine needle in the direction of transabdominal via the uterus finally into the amniotic sac to obtain fetal cells to culture & perform FISH genetic analysis