The normal physiologic mechanism used by G proteinlinked rec

The normal physiologic mechanism used by G protein–linked receptors is for a ligand to bind to the G protein–linked receptor; this in turn activates __________ located in the intracellular side of the plasma membrane, which eventually leads to the physiologic effector action.

Solution

Answer: diacylglycerol

Hydrophobic second messengers are water-insoluble molecules such as diacylglycerol, and phosphatidylinositols, which are membrane-associated and diffuse from the plasma membrane into the intermembrane space where they can reach and regulate membrane-associated effector proteins