GFill in the following table concerning primary and secondar

G)Fill in the following table concerning primary and secondary antibody responses:

Property

Primary response

Secondary response

Responding B cell

B cell isotype

Antigens

Antibody affinity

H)Describe how opsonization of pathogens occurs by antibodies. What is the effect of opsonization by antibodies?

I)What T cell subset would be stimulated by a virus? Why?

J)What are cell adhesion molecules (CAMS) and how are they used by leukocytes? Give an example of a cell adhesion molecule.

Solution

G) The following table is about the primary and secondary antibody responses:

Property

Primary response

Secondary response

Responding B cell

  naïve B-cell and T-cell

  memory cell

B cell isotype

IgM antibodies

Varies depending on antigen (IgG is mainly produced)

Antigens

Both thymus dependent and thymus independent antigens

Only thymus dependent antigens

Antibody affinity

Lower

Higher

H). Opsonization increasing phagocyte efficiency: “Opsonizing antibody –antigen complex” is a process of antibody marking that renders it for killing and digestion by phagocytes result in increase in phagocyte efficiency (thus, It may also cause bacteria lysis but the second option fits best). It is the process of an antigenic microbe is coated with antibodies to make it more susceptible to phagocytosis.