Question 6 of 6 Map a Sapling Learning this question was wri

Question 6 of 6 Map a Sapling Learning this question was written by Pavan Kadandale at University of California, Irvine macmillan learning Classify the reactions catalyzed by the following enzymes into ATP-consuming, ATP-generating, or Neither. ATP-consuming Neither ATP-generating Enolase Phosphoglycerate mutase Hexokinase Phosphoglycerate kinase Alcohol dehydrogenase Aldolase Pyruvate kinase Lactate dehydrogenase Phosphofructokinase

Solution

Enolase is neither ATP consuming nor ATP generating.It converts 2- phosphoglycerate into phospho Enol pyruvate during glycolysis.

Phosphoglycerate mutase is a ATP generating enzyme. It helps in the conversion of 1,3 Bis phosphoglycerate to 3, phosphoglycerate.The reaction is called substrate level phosphorylation.Two ATP are produced in this reaction.

Hexokinase is a ATP consuming enzyme.It converts Glucose into Glucose -6- ohosphate by the utilisation of energy.

Phosphoglycerate kinase is a ATP generating enzyme.It transfer phosphate from 1,3 Bis phosphoglycerate to ADP and 3-phosphoglycerate and ATP.There are two PKG in human body (PKG 1 and PKG 2).

Alcohal dehydrogenase is neither ATP generating nor ATP consuming. It helps in interconversion between alcohal and aldehyde or ketones with the reduction of NAD to NADH.

Aldolase is also neither ATP generating nor consuming. It converts fructose 1,6 bisposphate to Dihydroxy acetone and glyceraldehyde 3 phosphate.

Pyruvate kinase is a ATP generating enzyme as it converts PEP to pyruvate which is the end product of glycolysis. It is a substrate level phosphorylation.

Lactate dehydrogenase is neihter a ATP generating enzyme nor consuming. It converts lactate into pyruvate during fast muscle contraction and during hypoxia.It helps in CORI cycle which takes place in liver.

Phosphofructokinase is a ATP consuming enzyme.It converts fructose 6-phosphate into fructose 1,6 bis phosphate.