What is the most likely fate of a misfolded protein in the E

What is the most likely fate of a misfolded protein in the ER?

a. It is sequestered by the proteasome

b. It is tagged with ubiquitin in the ER and then degraded in the cytosol

c. It is moved out of the ER for its degradation in the cytosol

d. Its associations with many chaperones guarantee the correct folding of the protein

e. It is degraded by the proteasome in the ER lumen

Solution

The fate of a misfolded protein in the ER is that it can either get associated with many chaperones which will help guarantee the correct folding of the protein or if that does not happen it can be degraded in the ER lumen and autophagozed and lastly the misfolded protein can be moved out of the ER for its degradation in the cytosol which is ideally would happen to most of the misfolded proteins.