Put the following events concerning Phosphatidylinositollink

Put the following events concerning Phosphatidylinositol-linked signal transduction in the appropriate order as regards the sequence of events. (l) PLC cleaves PIP2 to IP3 and DAG. (2) Hormone binds to a specific receptor. (3) There is a GTP for GDP exchange on a G protein. (4) The GTP-G protein moves to a PL-C and activates it. (5) IP3 binds to an intracellular receptor and induces calcium release. (6) DAG and calcium fully activate protein kinase C. Question 21 options: A. 2, 3, 1, 4, 6, 5 B. 2, 3, 4, 1, 5, 6 C. 3, 2, 4, 1, 5, 6 D. 2, 4, 3, 1, 6, 5 E. 3, 4, 2, 1, 5, 6

Solution

(2) Hormone binds to a specific receptor

(3) There is a GTP for GDP exchange on a G protein

(4) The GTP-G protein moves to a PL-C and activates it

(l) PLC cleaves PIP2 to IP3 and DAG.

(5) IP3 binds to an intracellular receptor and induces calcium release.

(6) DAG and calcium fully activate protein kinase

SINCE IT IS A MEMORY BASED QUESTION SO IT DOESNT HAVE ANY EXPLINATION

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