What are possible results of inhibiting a NaK pump in a cell

What are possible results of inhibiting a Na/K pump in a cell with an excitable membrane? For the quiz, you will be given a list of choices, Choose all that apply, 2 points You\'ve just discovered an animal that uses Chloride (Cl-)instead of Sodium (Na+) to depolarize the cell (make the membrane potential less negative) during an action potential. In order for this to work, where would the concentration of Cl-need to be the highest, inside or outside the cell? (Be prepared to answer WHY on exam.) Sarcolemma:_____::sarcoplasm: cytoplasm The triad is a site where an electrical signal is converted into a chemical one within a muscle fiber. T/F ACh (and other neurotransmitters): ligand gated Na voltage gated Ca channel channel::_____: voltage gated Ca channel What is a motor unit composed of? In what kinds of muscle fibers (fast or slow twitch) would you expect to see higher concentrations myoglobin, glycogen, and mitochondria? For the exam, be prepared to explain those associations. For the quiz, this will be a matching question. Smooth muscle differs from skeletal muscle in ways that reveal the functions of cellular structures. What are some of those major differences? (For the quiz, you will identify a SIMILARITY between skeletal muscle fibers and smooth muscle myocytes. Use the book and my additional scanned lecture notes to help)

Solution

1. Cell membrane depolarizes.

2. Outside because of the negative charge.

3.muscle cell membrane .

4. F, its at neuromuscular junction.

5.Ach and endogenous dopamine.

6.Dendrite, cell body, nucleus , and axon.

7. Slow twitch muscle fibers as they contract slowly, so tire less like chicken leg.

8. Skeletal muscles are striated whereas smooth muscles are non striated.

References

1. Alberts,B., Johnson, A., Lewis, J., Raff, M., Roberts,K., & Walter, P. (2002). Ion Channels and the Electrical Properties of Membranes.Molecular Biology of the Cell. 4th edition. New York: Garland Science.

2. Agasti, T, K. (2010). Textbook of anasthesia for post graduates. New Delhi:Jaypee brothers medical publishers(P) Ltd