How is a vaccination WITH a live attenuated VIRAL VACCINE si
Solution
ANS:
During natural infection:
The immune system recognize the pathogen as foreign and makes immune response against to it. The pathogen which caused immune response is called as antigen.
The immune response of antigens create antibodies. This process is known as humoral immune response.
An antibodies are specific to antigen and it had ability to remember it, this nature of the antibodies helps in another attack of same or similar antigens tries to infect the person again and the immune response will be stronger and faster than by it protects persons from virus.
Live attenuated vaccine:
It is discovered by Louis Pasteur. In this the whole micro organism is cultured in such a way that it loses the virulence and the same time induce humoral and cell mediated response only few booster are required moderately stable but revert back to virulent form.
Mechanism: The antigen is injected resulting in primary response memory cells are formed upon express to the organism that natural condition the memory cells participate resulting in secondary response which is more effective than primary response.
It should not be given those who suffer from immune deficiency.
Ex: Sabin, MMR, yellow fever Vaccines and Rota virus Vaccine.
Conclusion: So according to the above immune mechanisms, live attenuated VIRAL VACCINE are similar to the natural immune response to a VIRAL INFECTION

