Homework SourseThe synthesis of Okazaki fragments during DNA replication re
The synthesis of Okazaki fragments during DNA replication requires:
The E. coli initiator protein, ___________, has four functional domains.
Which of the following DNA polymerases has very high proccessivity relative to the others?
The ____________ is made of two identical polypeptides that are encoded by dnaN.
| synthesis of a DNA primer by DNA primase |
| synthesis of an RNA primer by DNA primase |
| synthesis of a DNA primer by RNA polymerase |
| synthesis of an RNA primer by RNA polymerase |
| nothing is required, the DNA polymerase requires no primer |
Solution
1. Synthesis of Okazaki requires synthesis of RNA primers by DNA primase. Okazaki are small fragments tht are also called lagging strand which requires RNA primers.
2. DnaA is made up of four domains: the first is the N-terminal that associates with regulatory proteins, the second is a helical linker region, the third domain is a AAA+ region that binds to ATP, and the fourth domain is the C-terminal DNA binding region
3. DNA polymerase||| has high processivity
4. DNA N is involved in b clamp which is also called sliding clamp
