Phosphate groups can be transferred between adenosine phosph

Phosphate groups can be transferred between adenosine phosphates. One such example is as follows: 2ADP doubleheadarrow ATP + AMP, where Keq = 0.45 Calculate delta G degree\' for the reaction above If one mole of ADP is allowed to equilibrate at 295K, how many moles of ATP, ADP and AMP would you expect at equilibrium?

Solution

a) The delta G for ATP formation is +34.5 kJ/mole

Adenylate kinase removes the ADP when ADP accumulated in muscles during vigourous exercise. The reaction is reversible and the delta G is zero

2ADP <-----------------> ATP + AMP Go ’ 0