CHAPTER 6 ENzYMES Answer two of the questions 13 below 1 Dis

CHAPTER 6: ENzYMES. Answer two of the questions 1-3 below. 1. Discuss what it means for biological reactants to be in a metastable state. 2. Discuss How enzymes lower the activation energy of a spontaneous chemical reaction. 3. Discuss the role of amino acid R groups in the active site of an enzyme, specifically the roles of amino acids most likely to participate in the active site.

Solution

Ques-1:

The metastable nature of the reactant molecules is often relies upon the activation energy and if it is high then the proportion of energy is low so that these reactant molecules are highly reactive but have no stability under stable nature

Ques-2

Enzymes lower activation energy of reactant by forming an enzyme –substrate complex” and transition state so that the active site of enzyme reacts with the substrate finally causes conformation changes & reduction in free energy of enthalphy of reactants. So that the enzymes often reduce activation energy of a reactant to further proceed a spontaneous reaction from left to right