The frequency of mutations causing Duchennetype muscular dys

The frequency of mutations causing Duchenne-type muscular dystrophy in England is 105 per million gametes per generation. What is (use scientific notation and include units)?

Solution

Answer) stands for mutation rate which is a measure of frequency on which a wild type gene changes to a mutant type. this is generally expressed in terms of number of mutations occuring per biological unit. this biological unit can be mutations occuring per cell division, per gamete or per replication round in each generation. this is depicted in scientific notations as 10^x.

in the given case, we have frequency of DMD mutations as 105 per million gametes per generations.

convert 105 mutations per million gametes to scientific notations as following;

105 mutations per 1000000 gametes means 105 /1000000 mutations per gamete

or 1.05 x 10^-4 mutations per gamete

this mutation rate is occuring per generation.

so = 1.05 x 10^-4 mutations per gamete per generation