1 Consider a solution made up of 75 R and 25 S What is the e

1. Consider a solution made up of 75% R and 25% S. What is the enantiomeric excess (ee%) of the R enantiomer?

2. When 1 g of compound X is dissolved in 100 mL of solvent, the observed rotation is +12. What will be the observed rotation if 1 g of compound X is dissolved in 50 mL of solvent?

Solution

1) enantiomeric excess =( percent of major isomer) - ( percent of minor isomer)

percent of major isomer = 75% R

percent of minor isomer = 25% S

enantiomeric excess = = 75 - 25 = 50 %