which of the following is the most common humoral immune def

which of the following is the most common humoral immune deficiency disease

a. bruton aammaglobulinemia

b. iga defecience

c. wiskott-aldrich symdrome

d. selective iga definecncy

Solution

The most common humoral immuno deficiency disease is selective IgA deficiency.

Humoral immunodeficiency diseases are those that cause impaired humoral immunity (immunity mediated by B-cells)

Bruton agammaglobulinemia is a X-linked inherited immunodeficiency disease due to mutations in Bruton tyrosine kinase gene. As a result maturation of pre-B cells into mature B-cells doesnot occur.

Wiskott-Aldrich syndrome is X-linked recessive disorder which is rare and is characterized by thromobocytopenia (low blood platelet count), bloody diarrhea and eczema.

Selective IgA deficiency is also a genetic immunodeficiency disorder and is mostly asymptomatic. In people with this deficiency B-cells fail to secrete IgA antibody. As a result, the person is more susceptible to infections of respiratory and digestive tracts.