Select all of the properties related to collagen 1 Contain b

Select all of the properties related to collagen:

1) Contain binding sites for many other ECM proteins
2) Include a rich network of glycosaminoglycans
3) Mutations can cause diseases such as \"fibrosis\" and fragile bones
4) Most abundant protein in a human
5) Made of alpha-chains
6) Collagen heterotypes give unique mechanical properties to an ECM

Solution

Answer:

Include a rich network of glycosaminoglycans

Mutations can cause diseases such as \"fibrosis\" and fragile bones

Most abundant protein in a human

Collagen heterotypes give unique mechanical properties to an ECM

Reason:

Collagen is a protein, which is encoded by total 44 genes from gene expression into mRNA transcription in the nucleus. Further mRNA is going to be translated into more than 200 amino acid peptide on the ribosomes. This peptide is going to undergo various co-translational & post-translational protein- folding in “Endoplasmic reticulum lumen & Golgi apparatus” finally produces a mature protein. This is going to be transferred to vesicles where it undergoes 28 different types of collagen fibrils via Glycolysylation is the predominant process. The bone and cartilage are embedded within “lacunae” associated with extracellular matrix (ECM) and strengthened collagen. This is surrounded by fibrous connective tissue in which fibrinolectin and laminin associated with fibroblasts are located followed by mesenchyme. The collagen is composed of 25%to 35% human protein that has a rich network of glycosaminoglycans. Mutations in the synthesis of collagen can cause diseases such as \"fibrosis\" and fragile bones. Collagen heterotypes give unique mechanical properties to an ECM

Select all of the properties related to collagen: 1) Contain binding sites for many other ECM proteins 2) Include a rich network of glycosaminoglycans 3) Mutati

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