what assumptions are made in the application of toxicologica

what assumptions are made in the application of toxicological experiments to epidemiology?

Solution

In toxicology experiments, laboratory work related to animal and their control group, whereas epidemiology collects data abs interpret from the real world. Some problem with toxicological experiments, species to species variation, dose extrapolation (high to low), route in the body or delivery system and interaction network with other chemicals. Assumption comprises of assessment of the quality of material used, evaluation of weight of the evidence, collection of relevant study material during the study, Scalable data for the interpretation, Checking of the null hypothesis regarding no side effect on the health.