Homework Sourse1 For each of the following statements indicate whether you
1. For each of the following statements, indicate whether you think the statement is true or false. If you think the statement is false, indicate why.
a. B cells mature into effector B cells in thymus.
b. IgA is made against TI antigen.
c. In order to migrate to the boundary region B cells induce, whereas T cells inhibit CCR7 expression.
2. Contrast the role of FCRI, FCRI, and FCRIII.
Solution
T cells matured in a thymus.The B cells matured in the bone marrow.
So this statement is false.
IgA is made against TI antigen commensal bacteria ,is probably synthesized in TI manner.
The antibodies which are made against TI antigens are IgM.
So this statement is false.
Rest statement is true.
FcRI is the major receptor that mediates allergic inflammatory signaling in mast cells and basophils.
FcRII, is the \"low-affinity\" receptor for IgE, an antibody involved in allergy and resistance to parasites, and is important in regulation of IgE levels.
FcRIII receptors found on macrophages and stimulate the release of additional platelet-activating factor.
