Homework SourseWhich Isoform of pyruvate kinase would you target in order t
Which Isoform of pyruvate kinase would you target in order to suppress proliferation of tumor cells? And why?
Which Isoform of pyruvate kinase would you target in order to suppress proliferation of tumor cells? And why?
Solution
PKM2 isoform of pyruvate kinase is to be targeted to suppress tmour proliferation as it is highly expressed in the cells which have high rate of synthesis of DNA and RNA .Like Tumor cells ,embryonic cells.
