TRUE OR FALSE AND WHY d Binding of extracellular ligands to

TRUE OR FALSE AND WHY: d) Binding of extracellular ligands to receptor tyrosine kinases (RTKs) activates the intracellular catalytic domain by propagating a conformational change across the lipid bilayer through a single transmembrane helix. e) Calcium-induced calcium release is a phenomenon that describes how intracellular Ca2+ concentrations spike due to the release of Ca2+ through the IP3 channels in the ER membrane.

Solution

D. TRUE

Whenever a signal trnsduction takes place through the lipid bilayer, the signal is transmitted by inducing a conformational change in the receptor.

E. FALSE

intracellular calcium is regulated by adenylate cyclase pathway . Then calcium release is triggered by IP3