How is it that the signal for transmembrane transport and ve

How is it that the signal for transmembrane transport and vesicular transport active at different times?

Solution

This happens due to the presence of the specific protein peptide called Signal Sequence present with the protein which signal which protein is to be transmembrane protein and which had to be through vesicular transport..

For eg..

Signal Sequence of Di-acidic (Asp-X-Glu) gives a membrane protein signal from ER to Golgi... Similarly, Lys-Lys-X-X is also a membrane from Golgi to ER..!!

Signal Sequence of Lus-Asp-Glu-Leu is a vesicular transport protein of type-1 COP-1 vesicles type..

In this way the protein is differentiated from the respective transport..