1 In trimeric G proteins GTP binds to the alpha subunit the
1. In trimeric G proteins, GTP binds to:
the alpha subunit.
the beta subunit.
the gamma subunit.
the activated trimer.
2. Phosphatidylinositol 4,5-bisphosphate (PIP2) is cleaved by phospholipase C into:
1,2-diacylglycerol (DAG).
phosphatidylinositol (PI).
inositol 1,4,5-trisphosphate (IP3).
1,2-diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3)
3. 1,2-diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) are cleaved from phosphatidylinositol 4,5-bisphosphate (PIP2) by the enzyme:
adenylyl cyclase.
phosphodiesterase.
phospholipase C.
protein kinase C.
| a. | the alpha subunit. | |
| b. | the beta subunit. | |
| c. | the gamma subunit. | |
| d. | the activated trimer. |
Solution
In General protein coupled receptor the GTP binds to alpha subunit of the trimeric G protein. By the action of phospho lipase C , the given compound cleaved to diacylglecerol and inositol triphosphate. The enzyme is phospholipase C.