what happens if mutation causes the loss of checkpoint A mut

what happens if mutation causes the loss of checkpoint...

A mutation occurs that results in the loss of the \"checkpoint\" function of the mitotic centromere. Which of the following is a likely result of this mutation? a. Chromosome breakage b. Production of enviable gametes c. Premature initiation of anaphase d. Loss of the ends of chromosomes

Solution

Answer:

13. (c) Premature initiation of anaphase.

At cell cycle checkpoints, the cell cycle is controlled, ensuring that each stage of the cycle is completed before the next stage begins.

The checkpoint ensuring that chromosome segregation is correct is termed spindle assembly checkpoint (SAC), spindle checkpoint or mitotic checkpoint.

The spindle checkpoint prevents anaphase onset until all chromosomes are properly attached to the spindle. So, if this checkpoint looses its function, it will result in premature initiation of anaphase.