Which of the following is true Melanomas are especially mali

Which of the following is true? Melanomas are especially malignant because they are derived from a cell type that underwent an EMT, so they may reactivate this program more easily. The EMT cant he reversed, which is why metastases rarely resemble them primary tissues of origin. The Slug and Snail transcription factors are strong Inhibitors of the EMT. Neural crest cells are a particularly malignant class of tumor cells in the brain. Which of the following is true of MMPs? In carcinomas, most MMPs are produced by stromal cells rather than the tumor cells themselves. MMPs tend to degrade growth factors present in the ECM. All MMPs are membrane bound and therefore cleave substrates in the immediate vicinity of the cells that produce them. MMPs are normally expressed only during development, so MMP expression in adults is typically restricted only to tumorigenic processes. Which is true of cell motility? Lamellipodia are sheetlike structures that form at the trailing edge of motile cells. Filopodia are a subset of lamellipodia that fail to attach to the substrate and thus are swept back to the cell as membrane ruffles. Rae inactivation is required for the formation of lamellopodia. Epithelial cells can be induced to become motile by the scatter factor HGF.

Solution

Q7-a-True

b--False

C- True

d-True

8

1-True

2-true

3-False

4-False

9-

1-true

2-false

3-True

4-True