Question 1 In untreated insulindependent diabetes all these

Question 1) In untreated insulin-dependent diabetes, all these differences from the normal state are observed EXCEPT A. transport of glucose into adipose tissue is increased. B. gluconeogenesis is increased. C. glycogen breakdown in liver is increased. D. lipolysis in adipose tissue is increased. E. ketogenesis is increased. Question 2) Insulin A. stimulates the phosphodiesterase enzyme which breaks down cAMP. B. decreases the concentration of fructose-2,6-bisphosphate in liver. C. inhibits hepatic glycolysis. D. stimulates glucose transport into the liver. E. has the same effect on glycolysis in the liver as glucagon.

Solution

Ans 1 A transport of glucose into adiposd tissue is increased

Glucose is stored into muscle and adipose tissues during anabolic conditions when the concentration of blood is high. This glucose uptake is facilitated by insulin dependent GLUT enzymes. So this process is restricted in the case of insulin dependent diabetes.