a Calculate the number of FADH2 NADH and acetyl CoA molecule

a) Calculate the number of FADH2, NADH, and acetyl CoA molecules produced when a molecule of palmitate (16 Cs) is degraded by beta-oxidation. (2pts)

b) Following complete oxidation of the acetyl CoA molecules in the citric acid cycle and electron transport to oxygen, how many ATP will be produced from 1 palmitate? Be sure to show the source of all of your ATP and calculations. (Don’t forget to include all the products of beta-oxidation as well as the TCA cycle). (5pts)

Solution

1. Net ATP yield from one molecule of palmitic acid is shown as below:

Pathway ATP yield
Fatty acid spiral(Synthesis of palmitoyl CoA) -2
Krebs cycle 8
Oxidative phosphorylation
7NADH from fatty acid spiral 21
7FADH2 from fatty acid spiral 14
24NADH from citric acid cycle 72
8 FADH2 from citric acid cylce 16
Total 129
a) Calculate the number of FADH2, NADH, and acetyl CoA molecules produced when a molecule of palmitate (16 Cs) is degraded by beta-oxidation. (2pts) b) Followin

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