A Write out the beta oxidation pathway of CoA ester of docos

A. Write out the beta oxidation pathway of Co-A ester of docospentaenoic acid (DPA) (C22:5 Delta-cis- 7,10,13,16,19) You must draw the structure, write the enzyme name and additional products produced at each step You do not name the lipid structures B. CLEARLY MARK (AND COUNT) EACH ROUND OF BETA OXIDATION c. In a table, show the results name and amount of products produced) of each round of beta oxidation and give totals D. Calculate the ATP that is produced when the fatty acyl Co A is oxidized to CO_2 and H_2O. E. What is the effect of double bonds at odd carbons on the energy yield? F. What is the effect of double bonds at even carbons on the energy yield? G. Apply what you just learned: You have a C 12 fatty acyl CoA, what are you products of beta oxidation (remember you could continue on to calculate ATP yield) Now assume it is a C12:2 Delta3.6 acyl-CoA. What are you products of you oxidation. (remember you could continue on to calculate ATP yield.) Example table -DO NOT USE THIS ONE. YOU MUST MAKE YOUR OWN!

Solution

One cycle of B oxidation produces 1 NADH, 1 FADH2 and 1 acetyl CoA.

1 NADH produces 2.5 ATP, 1 FADH2 produces 1.5 ATP and 1 acetyl CoA produces 10 ATP. So the total ATP are 14 ATP. In activation 2 ATP are consumed so the net ATP is 12 ATP.