Dr Smith tells you that she loved biochemistry as an undergr

Dr. Smith tells you that she loved biochemistry as an undergrad, and with a grin, asks you to tell her whether fructose, galactose, or mannose would be a suitable treatment to help prevent the red blood cell death that results in Sarah\'s anemia. You do a quick mental calculation of the ATP yield you would predict for these sugars in RBCs that are completely deficient in pyruvate kinase activity. Which of these sugars would give a higher yield of ATP than glucose and thus be a potential treatment? a) fructose b) galactose c) mannose e)none of the above

The answer is NOT galactose.

Solution

Fructose of thEse sugars would give a higher yield of ATP than glucose and thus be a potential treatment because cells make ATP starting from sugars likE fructose and other high potential energy compounds due to here catabolism of sugars occurs when compared to others.