A clinical trial designed to show the efficacy of a new drug

A clinical trial designed to show the efficacy of a new drug in reducing progression lo hypertension reports the following: a) Compute the relative risk of progression to hypertension among patients receiving the drug as compared to the placebo.

Solution

Compute the relative risk of progression to hypertension among patients receiving the new drug as compared to the placebo. Explain what this calculated value means concretely

RR=(28X200)I(38X 200)= 14/19=0.7368
The calculated value shows that 73.68% of the patients have the relative risk of progression to hypertension.

Compute the odds ratio of progression to hypertension among patients receiving the new drug as compared to the placebo.
OR= (28 X 162) /(172X 38) = 0.6940

=69.4%

The calculated value shows that 69.4% of the patients have the relative risk of the patient receiving new drug compared to placebo.