Chris conducted an experiment to test whether the P53 expres

Chris conducted an experiment to test whether the P53 expression is different between colon cancer and normal issues. He decided to use each participant as his/her own control. He recruited 10 colon cancer patients and measured the P53 expression levels on both normal and cancer tissues for each of the 10 patients. What test should he use to analyze the data? Why?

Solution

For the comparision of levels on both normal cancer tissues, \"Chi-square test for indepedence of attributes\" is suitable.

The test is applied when you have two categorical variables from a single population. It is used to determine whether there is a significant association between the two variables.

Here, levels of normal tissues and levels of cancer tissues are categorical variables.