Complete the following statements about solutions of mammali

Complete the following statements about solutions of mammalian myoglobin or hemoglobin by marking the appropriate choice on your Scantron sheet. The decrease in O_2 of a solution of myoglobin will [A) increase B) decrease C) not change] the pH of the solution. An increase in the concentration of CO_2 in a solution of hemoglobin will [A) increase/B) decrease/C) not change] the number of protons bound to the hemoglobin An increase in the concentration of O_2 in a solution of hemoglobin will [A) increase/B) decrease/C not change] the average pKa of hemoglobin. An increase in pH of a solution of hemoglobin will [A) increase/B) decrease/C) not change] the amount of bisphosphoglycerate (BPG) bound by hemoglobin in the solution.

Solution

Answer: (14) The decrease in oxygen level in solution of myoglobin will decrease pH in solution because lower oxygen level will have higher hydrogen ion concentration and higher CO₂ will decrease pH level of solution.

(15) An increase in concentration of CO₂ in solution of haemoglobin will increase number of protons bound to haemoglobin.This happens as high concentration of CO₂ releases bicarbonate and protons which binds to haemoglobin making it to release oxygen to surrounding tissues.

(16) An increase in the concentration of O₂ in a solution of haemoglobin will decrease the average pKa of haemoglobin.

(17) An increase in pH of solution of haemoglobin will decrease the amount of biphosphoglycerate bound by haemoglobin in solution beacuse increase in pH level will increase affinity for oxygen in haemoglobin while the presence of diphosphoglycerate stabilises the T state of deoxyhaemoglobin which decreases haemoglobin\'s affinity for oxygen.